Police were called to Pepper Street yesterday (credit: Google Maps)
Officers were called to a disturbance in Pepper Street at 5.47pm where the three injured men were found with stab injuries.
No arrests have been made.
None of the males suffered life-threatening injuries.
As police continue investigations, a crime scene remains in place.
A Section 60 is also in place for the E14 area until 9am this morning.
This gives officers additional powers to use stop and search to prevent any further violence.
Any witnesses are asked to call 101 quoting CAD 6042/19Jul.
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Tags: Isle of Dogs, Metropolitan Police, Stabbing, Met Police