The 19-year-old remains in a stable condition after he was found in Longbridge Road just after 2.30am.
Two other people suffered minor injuries during the incident.
No arrests have been made and enquiries continue.
The area remains closed off in both directions closed between Fanshawe Avenue and South Park Drive with an number of buses on diversion
Anyone with information can call police on 101.
We await an update on this breaking story.
Tags: BarkingMale, aged 19, being treated in hospital following stabbing in Longbridge Road, Barking at approximately 230am. His condition is stable. Two others found with minor injuries. No arrests. Enquiries continue.
— Barking & Dagenham Police (@MPSBarkDag) September 25, 2018